Acadvl - acyl-CoA dehydrogenase, very long chain Gene

Also Known as VLCAD

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25363

Summary

Enables fatty-acyl-CoA binding activity; flavin adenine dinucleotide binding activity; and very-long-chain-acyl-CoA dehydrogenase activity. Involved in fatty acid beta-oxidation. Located in mitochondrial inner membrane. Biomarker of non-alcoholic fatty liver disease. Human ortholog(s) of this gene implicated in very long chain acyl-CoA dehydrogenase deficiency. Orthologous to human ACADVL (acyl-CoA dehydrogenase very long chain). [provided by Alliance of Genome Resources, Apr 2022]

Acadvl Products (1)

mRNA Protein Name
NM_012891.2 NP_037023.1 very long-chain specific acyl-CoA dehydrogenase, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables acyl-CoA dehydrogenase activity IDA
IDA: Inferred from direct assay
8034667 RGD
enables fatty-acyl-CoA binding IDA
IDA: Inferred from direct assay
1730632 RGD
enables flavin adenine dinucleotide binding IDA
IDA: Inferred from direct assay
1730632 RGD
enables long-chain fatty acyl-CoA dehydrogenase activity IDA
IDA: Inferred from direct assay
8034667 RGD
enables very-long-chain fatty acyl-CoA dehydrogenase activity IDA
IDA: Inferred from direct assay
1730632 RGD
Biological Process GO Annotation Evidence References Source
involved in fatty acid beta-oxidation IDA
IDA: Inferred from direct assay
8034667 RGD
Cellular Component GO Annotation Evidence References Source
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
1730632 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

very long-chain specific acyl-CoA dehydrogenase, mitochondrial

  • VLCAD very-long-chain acyl-CoA dehydrogenase

  • Very long chain Acyl-Coa dehydrogenase

  • acyl-Coenzyme A dehydrogenase, very long chain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00131 ACADVL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-183318 PPARα/δ agonist 4 Agonist / Unkown
HY-RS19760 Acadvl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26257 Acadvl Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Acadvl NCBI NCBI:37