CYP2C8 - Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 Gene

Also Known as Cyp2c39

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29298

Summary

Predicted to enable heme binding activity and monooxygenase activity. Involved in several processes, including response to ethanol; response to lipopolysaccharide; and response to retinoic acid. Located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Orthologous to human CYP2C8 (Cytochrome P450 family 2 subfamily C member 8). [provided by Alliance of Genome Resources, Apr 2022]

CYP2C8 Products (2)

mRNA Protein Name
NM_017158.2 NP_058854.1 cytochrome P450 2C7 precursor
NM_017158.2 NP_058854.1 cytochrome P450 2C7 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to ethanol IEP
IEP: Inferred from expression pattern
10660124 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
8435092 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
8534269 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
8471063 RGD
involved in response to peptide hormone IEP
IEP: Inferred from expression pattern
10660124 RGD
involved in response to retinoic acid IEP
IEP: Inferred from expression pattern
9202400 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
15634872 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome P450 2C7

  • CYPIIC7

  • P450F

  • PTF1

  • cytochrome P450 2C7-like

  • cytochrome P450, 2c39

  • cytochrome P450F

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-17356 Fenofibrate 99.97% Yes

Pre-clinical Phase

Bioactive Molecules (50)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-129993 Gemfibrozil 1-O-β-glucuronide Inhibitor 99.87% Unkown
HY-N0319 Salvianolic acid C Inhibitor 99.94% Unkown
HY-W013268 (S)-(+)-N-3-Benzylnirvanol Inhibitor 99.76% Unkown
HY-114759 MS-PPOH Inhibitor 99.05% Unkown
HY-100641 4-Hydroxytolbutamide 99.69% Unkown
HY-148352 BAY-4931 Antagonist 98.72% Unkown
HY-163996 DD202-114 99.27% Unkown
HY-100641S 4-Hydroxytolbutamide-d9 99.29% Unkown
HY-125348 6α-Hydroxy paclitaxel 99.93% Unkown
HY-135335 3'-Hydroxy Repaglinide 98.20% Unkown
HY-135334 ACP-5862 Inhibitor 98.32% Unkown
HY-70002AS N-Desmethyl enzalutamide-d6 Antagonist 97.95% Unkown
HY-135331 N-Desmethyl-Apalutamide 99.08% Unkown
HY-116862 Dibenzylfluorescein 99.54% Unkown
HY-147294 Nivasorexant 99.74% Unkown
HY-17356R Fenofibrate (Standard) 99.92% Unkown
HY-W587878 Thujopsene 86.31% Unkown
HY-163438 BKIDC-1553 Inhibitor 99.65% Unkown
HY-17356S Fenofibrate-d6 99.70% Unkown
HY-N5132 (-)-Fenchone 98.0% Unkown
HY-135335S 3'-Hydroxy Repaglinide-d5 99.46% Unkown
HY-147422 Xininurad Inhibitor 99.59% Unkown
HY-N6065 Praeruptorin A 99.57% Unkown
HY-W754151 N-Desmethyl apalutamide-d4 99.63% Unkown
HY-124542 5-Hydroxydiclofenac Inducer 99.52% Unkown
HY-135810 Cletoquine Inhibitor / Unkown
HY-135810A Cletoquine oxalate Inhibitor 99.63% Unkown
HY-141530 Clopidogrel-β-D-glucuronide Inhibitor / Unkown
HY-117160 4-trans-Hydroxy-glibenclamide Inhibitor 99.0% Unkown
HY-125348S 6α-Hydroxy Paclitaxel-d5 99.31% Unkown
HY-W067374 Aripiprazole impurity 38 97.79% Unkown
HY-125421 11β-HSD1-IN-26 Inhibitor / Unkown
HY-100641S1 4-Hydroxytolbutamide-d9-1 / Unkown
HY-10575 MK-5596 / Unkown
HY-135331S N-Desmethyl-Apalutamide-15N,d4 / Unkown
HY-135335S1 3'-Hydroxy Repaglinide-d7 / Unkown
HY-135810S Cletoquine-d4 Inhibitor / Unkown
HY-135810S1 Cletoquine-d4-1 Inhibitor / Unkown
HY-155376 mTOR inhibitor-14 Inhibitor / Unkown
HY-17356G Fenofibrate (GMP) / Unkown
HY-17356S1 Fenofibrate-d4 / Unkown
HY-181798 pKal-IN-1 Inhibitor / Unkown
HY-183149 BPN-37440 Inhibitor / Unkown
HY-183268 TRPM4-IN-4 Inhibitor / Unkown
HY-RS03459 CYP2C8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W699866 Gemfibrozil 1-O-β-glucuronide-d6 / Unkown
HY-W777442 Cletoquine-d4 Oxalate Inhibitor / Unkown
HY-119311 Ketopioglitazone Agonist / Unkown
HY-135334S ACP-5862-d4 Inhibitor / Unkown
HY-17356S2 Fenofibrate-13C6 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CYP2C8 NCBI NCBI:1558