Aaas - aladin WD repeat nucleoporin Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 300259

Summary

Predicted to be involved in microtubule bundle formation; mitotic spindle assembly; and nucleocytoplasmic transport. Predicted to act upstream of or within fertilization and learning. Predicted to be located in cytosol; microtubule cytoskeleton; and nucleus. Predicted to be part of nuclear pore. Human ortholog(s) of this gene implicated in achalasia and triple-A syndrome. Orthologous to human AAAS (aladin WD repeat nucleoporin). [provided by Alliance of Genome Resources, Apr 2022]

Aaas Products (1)

mRNA Protein Name
NM_001106795.1 NP_001100265.1 aladin
Protein Preferred Names Protein Names

aladin

  • achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A)

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0130R Perindopril (Standard) Inhibitor 99.92% Unkown

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-160187 AAA Antagonist 99.52% Phase 4
HY-12861 CB-5083 Inhibitor 99.90% Phase 1

Pre-clinical Phase

Bioactive Molecules (27)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-122632 Ciliobrevin D Inhibitor 99.37% Unkown
HY-119254 BAY-850 Inhibitor 98.93% Unkown
HY-123872 MSC1094308 Inhibitor 99.89% Unkown
HY-132158 MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin 96.17% Unkown
HY-111548 Spastazoline Inhibitor 98.50% Unkown
HY-148900 SCFSkp2-IN-2 Inhibitor 99.01% Unkown
HY-146074 RUVBL1/2 ATPase-IN-1 Inhibitor 99.63% Unkown
HY-145147 AAA-10 Inhibitor 99.97% Unkown
HY-100817 Rbin-2 Inhibitor 98.0% Unkown
HY-N6660 Trisdecanoin Inhibitor 98.0% Unkown
HY-Q04764 TI17 95.97% Unkown
HY-132159 MC-AAA-NHCH2OCH2COOH 98.56% Unkown
HY-132160 7-Aminomethyl-10-methyl-11-fluoro camptothecin 99.24% Unkown
HY-119254A trans-BAY-850 Control 99.30% Unkown
HY-122198 ML367 Inhibitor 99.84% Unkown
HY-132160A 7-Aminomethyl-10-methyl-11-fluoro camptothecin TFA 96.52% Unkown
HY-124776 NPD8733 Inhibitor 99.92% Unkown
HY-18398 N6-Threonylcarbamoyladenosine 99.62% Unkown
HY-P4460 AAA-pNA 98.29% Unkown
HY-160187A (Rac)-AAA 99.02% Unkown
HY-124253 SMDC818909 Inhibitor / Unkown
HY-145147A AAA-10 formic Inhibitor / Unkown
HY-RS00015 AAAS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-118460 ACJI-99C Inhibitor / Unkown
HY-182141 AAA Trimer phosphoramidite / Unkown
HY-B0130S1 Perindopril-d5 Inhibitor / Unkown
HY-D2376 BH-Vis / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aaas NCBI NCBI:8086