Ciliobrevin D

Ciliobrevin D purchased from MedChemExpress. Usage Cited in: Exp Neurol. 2025 May 8:115285. [Abstract]

Effect of Ciliobrevin D (5.7 μL at 90 μM, yielding a final concentration of 15 μM), a cytoplasmic dynein inhibitor, on AAV.CAP-B10 hippocampal transduction following cerebral lateral ventricle (CLV) injection. (a-f) Representative fluorescence images from indicated hippocampal regions in C57BL/6 mice intra-cerebroventricluarly injected with AAV.CAP-B10 alone (a-c) or co-administered with Ciliobrevin D (d-f). Blue fluorescence denotes the DAPI nuclear staining.

Ciliobrevin D purchased from MedChemExpress. Usage Cited in: J Virol. 2021 Feb 24;95(10):e02436-20. [Abstract]

Ciliobrevin D (20 μM) inhibited CSFV entry. PK-15 cells were pretreated with Ciliobrevin D (μM) and dimethyl sulfoxide (DMSO) at 37°C for 1 h and inoculated with CSFV (MOI = 10) at 4°C for 1 h and then shifted to 37°C for endocytosis. At 0, 1, 2, and 6 hpi, cell cultures were harvested for RT-qPCR.

Ciliobrevin D purchased from MedChemExpress. Usage Cited in: Development. 2024 Jul 1;151(13):dev202476. [Abstract]

Whole-mount in situ hybridization analysis of cmyb/I> and flk1 expression in the AGM region of zebrafish embryos at 28 hpf after treatment with DMSO (control), with BF170 alone, with the AAA+ATPase motor cytoplasmic dynein inhibitor Ciliobrevin D (CBD, blocking cilia function) (10 μM) or co-treated with CBD and BF170 (red arrowheads indicate positive signals). Box and whisker plot shows quantification of the whole-mount in situ hybridization data. Scale bars: 100 μm.