Pon3 - paraoxonase 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 312086

Summary

Enables 3,4-dihydrocoumarin hydrolase activity and arylesterase activity. Involved in coumarin catabolic process and phenylacetate catabolic process. Located in extracellular space and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in Alzheimer's disease; amyotrophic lateral sclerosis; and atherosclerosis. Orthologous to human PON3 (paraoxonase 3). [provided by Alliance of Genome Resources, Apr 2022]

Pon3 Products (1)

mRNA Protein Name
NM_001004086.1 NP_001004086.1 serum paraoxonase/lactonase 3 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables arylesterase activity IDA
IDA: Inferred from direct assay
12946270 RGD
enables dihydrocoumarin hydrolase activity IDA
IDA: Inferred from direct assay
12946270 RGD
Biological Process GO Annotation Evidence References Source
involved in coumarin catabolic process IDA
IDA: Inferred from direct assay
12946270 RGD
involved in phenylacetate catabolic process IDA
IDA: Inferred from direct assay
12946270 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
19091700 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serum paraoxonase/lactonase 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10874 PON3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21411 Pon3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27930 Pon3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pon3 NCBI NCBI:5446