Agl - amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 362029

Summary

Enables 4-alpha-glucanotransferase activity; amylo-alpha-1,6-glucosidase activity; and carbohydrate binding activity. Involved in glycogen catabolic process; response to glucocorticoid; and response to nutrient. Located in sarcoplasmic reticulum. Used to study uremia. Human ortholog(s) of this gene implicated in glycogen storage disease III. Orthologous to human AGL (amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase). [provided by Alliance of Genome Resources, Apr 2022]

Agl Products (1)

mRNA Protein Name
NM_001108564.1 NP_001102034.1 glycogen debranching enzyme

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables 4-alpha-glucanotransferase activity IDA
IDA: Inferred from direct assay
6449198 RGD
enables amylo-alpha-1,6-glucosidase activity IDA
IDA: Inferred from direct assay
6449198 RGD
enables carbohydrate binding IDA
IDA: Inferred from direct assay
6449198 RGD
Biological Process GO Annotation Evidence References Source
involved in glycogen catabolic process IDA
IDA: Inferred from direct assay
6449198 RGD
involved in glycogen catabolic process IMP
IMP: Inferred from mutant phenotype
9281456 RGD
involved in response to glucocorticoid IDA
IDA: Inferred from direct assay
120213 RGD
involved in response to hormone IDA
IDA: Inferred from direct assay
1413626 RGD
involved in response to nutrient IDA
IDA: Inferred from direct assay
1413626 RGD
Cellular Component GO Annotation Evidence References Source
located in sarcoplasmic reticulum IDA
IDA: Inferred from direct assay
15180797 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycogen debranching enzyme

  • amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (glycogen debranching enzyme, glycogen storage disease type III)

  • amylo-1,6-glucosidase, 4-alpha-glucanotransferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13805 PP2 Inhibitor 98.34% Unkown
HY-13804 PP1 99.57% Unkown
HY-112720 AGL-2263 Inhibitor 98.31% Unkown
HY-13805R PP2 (Standard) Inhibitor 99.05% Unkown
HY-144584 AGL-0182-30 / Unkown
HY-RS00449 AGL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-112350 AGL 2043 Inhibitor / Unkown
HY-P1364 Pep1-AGL Control / Unkown
HY-RS17356 Agl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23810 Agl Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27209 Btg2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Agl NCBI NCBI:178