VWC2 - von Willebrand factor C domain containing 2 Gene

Homo sapiens

Also known as UNQ739; PSST739

Gene ID: 375567 | Gene type: protein coding

About VWC2

Cytogenetic location: 7p12.2 Genomic coordinates (GRCh38): 7:49,773,638-49,922,205 (from NCBI)

This gene has 1 transcript (splice variant), 201 orthologues and 19 paralogues. Biased expression in heart (RPKM 2.5), ovary (RPKM 2.4) and 3 other tissues.

Summary

This gene encodes a secreted bone morphogenic protein antagonist. The encoded protein is possibly involved in neural function and development and may have a role in cell adhesion.[provided by RefSeq, Oct 2009]

VWC2 Products(1)

mRNA	Protein	Name
NM_198570.5	NP_940972.2	brorin precursor

VWC2 Protein Structure

VWC

0
100
200
300
325 a.a.

Protein Preferred Names

Protein Names

brorin

brain-specific chordin-like protein

Recombinant VWC2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77506	Brorin/VWC2 Protein, Human (HEK293, His)	Q2TAL6 (S28-M325)	≥95%

Related Diseases

Diseases

Alias

Tarsal-Carpal Coalition Syndrome

TCC	Tarsal Carpal Coalition Syndrome
Nog-Related-Symphalangism Spectrum Disorder

Craniodiaphyseal Dysplasia

CDD	Schaefer Stein Oshman Syndrome
Craniodiaphyseal Dysplasia, Dominant	Dominantly Inherited Craniodiaphyseal Dysplasia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15732	VWC2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	VWC2	MGD	MGI:2442987
Canis familiaris	VWC2	VGNC	VGNC:52060
Rattus norvegicus	VWC2	RGD	RGD:1589624
Felis catus	VWC2	VGNC	VGNC:102729
Bos taurus	VWC2	VGNC	VGNC:36857
Macaca mulatta	VWC2	VGNC	VGNC:108452
Others	VWC2	NCBI