PDE4A - phosphodiesterase 4A Gene

Species: Sus scrofa

Gene Type: protein coding
Gene ID: 396825

About PDE4A

Primary_assembly 2: 69,225,708-69,266,702 forward strand.Sscrofa11.1:CM000813.5

This gene has 3 transcripts (splice variants), 261 orthologues and 20 paralogues. Ubiquitous expression in heart (RPKM 7.2), subcutaneous adipose (RPKM 7.) and 8 other tissues.

PDE4A Products (1)

mRNA Protein Name
NM_001123159.1 NP_001116631.1 cAMP-specific 3',5'-cyclic phosphodiesterase 4A

PDE4A Protein Structure

PDE4_UCR

PDE4_UCR: pfam18100 (177 - 292)

PDEase_I

PDEase_I: pfam00233 (432 - 672)

  • 0
  • 200
  • 400
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  • 800
  • 859 a.a.
Protein Preferred Names Protein Names

cAMP-specific 3',5'-cyclic phosphodiesterase 4A

  • cyclic AMP-specific phosphodiesterase SSPDE4A1A

  • phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila)

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B1639 Enoximone Inhibitor 99.91% Unkown

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-108047 MK-0873 Inhibitor 95.0% Phase 2
HY-106003 GSK356278 Inhibitor 99.82% Phase 1

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-119190 PF-06445974 Inhibitor 98.59% Unkown
HY-16900A (R)-(-)-Rolipram Inhibitor 99.91% Unkown
HY-103050 ML-030 Inhibitor 99.28% Unkown
HY-131707 LEO 39652 Inhibitor 99.51% Unkown
HY-131340 LASSBio-1632 Inhibitor / Unkown
HY-114052 NVP-ABE171 Inhibitor / Unkown
HY-122167 L-869298 Inhibitor / Unkown
HY-134937 BC8-15 Inhibitor / Unkown
HY-179504 PDE4B-IN-6 Inhibitor / Unkown
HY-201403 LY2775240 Inhibitor / Unkown
HY-RS10220 PDE4A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10221 Pde4a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10222 Pde4a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PDE4A NCBI NCBI:5141