RXFP3 - relaxin family peptide receptor 3 Gene

Homo sapiens

Also known as SALPR; RLN3R1; RXFPR3; GPCR135

Gene ID: 51289 | Gene type: protein coding

About RXFP3

Cytogenetic location: 5p13.2 Genomic coordinates (GRCh38): 5:33,936,386-33,938,918 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 101 orthologues and 7 paralogues.

Summary

Predicted to enable G protein-coupled peptide receptor activity. Involved in positive regulation of cytokinesis. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

RXFP3 Products(1)

mRNA	Protein	Name
NM_016568.3	NP_057652.1	relaxin-3 receptor 1

RXFP3 Protein Structure

7tm_1

0
100
200
300
400
469 a.a.

Protein Preferred Names

Protein Names

relaxin-3 receptor 1

G-protein coupled receptor GPCR135

Related Diseases

Diseases

Alias

Schizotypal Personality Disorder

Schizotypal Personality

Chromosome 5p13 Duplication Syndrome

5p13 Microduplication Syndrome	Trisomy 5p13
Dup(5)(P13)

Chondroid Chordoma

Radiation Cystitis

Irradiation Cystitis

Chordoid Meningioma

Meningioma, Chordoid

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-150700	RLX-33	Modulator	99.79%	Unkown
HY-145278	RXFP3/4 agonist 2		99.82%	Unkown
HY-111583	RXFP3/4 agonist 1		/	Unkown
HY-145279	RXFP3 agonist 1		/	Unkown
HY-RS12359	RXFP3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	RXFP3	MGD	MGI:2441827
Felis catus	RXFP3	VGNC	VGNC:64833
Rattus norvegicus	RXFP3	RGD	RGD:1311550
Bos taurus	RXFP3	VGNC	VGNC:58407
Macaca mulatta	RXFP3	VGNC	VGNC:110436

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