Smpdl3a - sphingomyelin phosphodiesterase, acid-like 3A Gene

Also Known as ASM3A; ASML3; ASML3A; 0610010C24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57319

Summary

Predicted to enable phosphoric diester hydrolase activity and zinc ion binding activity. Predicted to be involved in nucleoside triphosphate catabolic process. Located in extracellular space. Is expressed in ovary and ureteric tip. Orthologous to human SMPDL3A (sphingomyelin phosphodiesterase acid like 3A). [provided by Alliance of Genome Resources, Apr 2022]

Smpdl3a Products (1)

mRNA Protein Name
NM_020561.2 NP_065586.3 acid sphingomyelinase-like phosphodiesterase 3a precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in negative regulation of cGAS/STING signaling pathway IMP
IMP: Inferred from mutant phenotype
37890481 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
26095358 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
25288789 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acid sphingomyelinase-like phosphodiesterase 3a

  • ASM-like phosphodiesterase 3a

Recombinant Smpdl3a Proteins

Cat. No. Product Name Accession Purity
HY-P77209 SMPDL3A Protein, Mouse (HEK293, His) P70158/NP_065586.3 (V23-L445) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13451 SMPDL3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20650 Smpdl3a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27161 Smpdl3a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smpdl3a NCBI NCBI:10924