MOGS - mannosyl-oligosaccharide glucosidase Gene

Also Known as DER7; GCS1; CDG2B; CWH41

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 7841

Summary

This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

MOGS Products (1)

mRNA Protein Name
NM_006302.3 NP_006293.2 mannosyl-oligosaccharide glucosidase isoform 1
Protein Preferred Names Protein Names

mannosyl-oligosaccharide glucosidase

  • epididymis secretory sperm binding protein

  • glucosidase I

  • processing A-glucosidase I