MOGS - mannosyl-oligosaccharide glucosidase Gene
Also Known as DER7; GCS1; CDG2B; CWH41
Species: Homo sapiens (human)
Summary
This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
MOGS Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_006302.3 | NP_006293.2 | mannosyl-oligosaccharide glucosidase isoform 1 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
mannosyl-oligosaccharide glucosidase |
|
|