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Cat. No.: HY-146656

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Glyoxalase I inhibitor 4

Glyoxalase I inhibitor 4 (compound 14) is a potent glyoxalase I inhibitor with an K_i of 10 nM.

For research use only. We do not sell to patients.

CAS No.: 250155-72-7
Formula: C₁₇H₂₁IN₄O₈S
Molecular Weight:568.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Glyoxalase I inhibitor 4 Chemical Structure

CAS No.: 250155-72-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Glyoxalase I inhibitor 4 (compound 14) is a potent glyoxalase I inhibitor with an K_i of 10 nM^[1].

IC₅₀ & Target

K_i: 10 nM (GLO1)^[1]

Chemical Information

CAS No. 250155-72-7
Molecular Weight 568.34
Formula C₁₇H₂₁IN₄O₈S
SMILES

N[C@H](C(O)=O)CCC(N[C@H](C(NCC(O)=O)=O)CSC(N(C1=CC=C(C=C1)I)O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jin T,et al. Recent advances in the discovery and development of glyoxalase I inhibitors. Bioorg Med Chem. 2020 Feb 15;28(4):115243. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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