country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-170646

Copy Link Print Information

Influenza A virus-IN-15

Influenza A virus-IN-15 (Compound 9b), a quinoline derivative, is a broad-spectrum inhibitor of influenza A viruses with acceptable cytotoxicity (IC₅₀: 0.88-6.33 μM). Influenza A virus-IN-15 can inhibit the transcription and replication of viral RNA and is used in research for its antiviral effects against influenza A viruses (IAV).

For research use only. We do not sell to patients.

CAS No.: 3075733-28-4
Formula: C₂₉H₃₀N₆O₃
Molecular Weight:510.59

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Influenza A virus-IN-15 Chemical Structure

CAS No.: 3075733-28-4

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

IC50: 0.88 μM (IAV)^[1].

In Vitro

Influenza A virus-IN-15 (Compound 9b) can inhibit the activity of IAV with an IC₅₀ value of 0.88 μM^[1].
Influenza A virus-IN-15 effectively inhibits the infection of A/Puerto Rico/8/34(H1N1), A/Aichi/2/1968(X31)(H3N2), B/Brisbane/60/2008(B/Victoria), and B/Phuket/3073/2013(B/Yamagata) strains in a dose-independent manner, with IC⁵⁰ values of 3.57 μM, 4.66 μM, 5.16 μM, and 6.33 μM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3075733-28-4
Molecular Weight 510.59
Formula C₂₉H₃₀N₆O₃
SMILES

O=C(CN1CCN(C2=NC(C(OCC(NCC3=CC=CC=C3)=O)=CC=C4)=C4C=C2)CC1)NC5=NC=CC=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Li H, Zhao J, et al. Synthesis and biological evaluation of substituted quinolines containing piperazine moieties against Influenza A virus[J]. Bioorganic & Medicinal Chemistry Letters, 2024: 130081. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote