1. Anti-infection
  2. Influenza Virus
  3. Influenza virus-IN-3

Influenza virus-IN-3 

Cat. No.: HY-146000
Handling Instructions

Influenza virus-IN-3 (compound 9) is a potent and selective influenza virus inhibitor with IC50s of 0.88, 0.10, 5.5, 0.51 µM for H5N1, H5N2, H5N6, H5N8, respectively. Influenza virus-IN-3 shows antiviral and NA (neuraminidase enzyme)-inhibitory activity. Influenza virus-IN-3 shows low cytotoxicity with an CC50 of >200 µM.

For research use only. We do not sell to patients.

Influenza virus-IN-3 Chemical Structure

Influenza virus-IN-3 Chemical Structure

CAS No. : 2412451-16-0

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Description

Influenza virus-IN-3 (compound 9) is a potent and selective influenza virus inhibitor with IC50s of 0.88, 0.10, 5.5, 0.51 µM for H5N1, H5N2, H5N6, H5N8, respectively. Influenza virus-IN-3 shows antiviral and NA (neuraminidase enzyme)-inhibitory activity. Influenza virus-IN-3 shows low cytotoxicity with an CC50 of >200 µM[1].

IC50 & Target

IC50: 0.88 µM (H5N1); 0.10 µM (H5N2); 5.5 µM (H5N6); 0.51 µM (H5N8)[1]

In Vitro

Influenza virus-IN-3 (compound 9a) shows NA (neuraminidase enzyme)-inhibitory activity with IC50s of 118.17, 1442.6, 34543.33, 78.06, 10206, 0.00048, 0.01222 nM for H5N1, H5N2, H5N6, H5N8, H5N1eH274Y, N1 (H1N1pdm09) and N2 (H3N2), respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

456.60

Formula

C25H32N2O4S

CAS No.
SMILES

O=C(C1=C[[email protected]@H](OC(CC)CC)[[email protected]](NC(C)=O)[[email protected]@H](NCC2=CC=C(C3=CSC=C3)C=C2)C1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Influenza virus-IN-3
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HY-146000
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