Penicillin-Streptomycin (100×), Sterile
Based on 100 publication(s) in Google Scholar
MCE Penicillin-Streptomycin (100×), Sterile is used to prevent bacterial contamination of cell culture due to their effective combined action against gram-positive and gram-negative bacteria, which contains 10,000 units/mL of penicillin and 10 mg/mL of streptomycin.
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Storage :
Stored at -20°C, and is stable for 1 year.
Description & Advantages
Penicillin interferes with the final stage of synthesis of the bacterial cell wall. Streptomycin inhibits elongation at transpeptidation step during protein synthesis and binds to 30S subunit, causing misreading.
MCE Penicillin-Streptomycin (100×) is a liquid formulation which contains 10,000 units/mL of penicillin and 10 mg/mL of streptomycin in 0.9% NaCl. The common working concentration is 100 units/mL for penicillin and 100 μg/mL for streptomycin.
Protocol
Thaw product at room temperature, and add it in a 1:100 (v/v) ratio to cell culture medium.
Publications
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Journal Impact Factor
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Most Recent
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Cell MetabHigh dietary fructose promotes hepatocellular carcinoma progression by enhancing O-GlcNAcylation via microbiota-derived acetate. [Abstract]2023 Nov 7;35(11):1961-1975.e6. PMID: 37797623
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Cell Mol ImmunolRBM25 is required to restrain inflammation via ACLY RNA splicing-dependent metabolism rewiring. [Abstract]2024 Nov;21(11):1231-1250. PMID: 39251781
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TheranosticsInhibition of macrophage inflammasome assembly and pyroptosis with GC-1 ameliorates acute lung injury. [Abstract]2025 Jan 20;15(6):2360-2374. PMID: 39990234
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OncogeneUSP33 facilitates the ovarian cancer progression via deubiquitinating and stabilizing CBX2. [Abstract]2024 Oct;43(43):3170-3183. PMID: 39256572
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OncogeneGSK3β and UCHL3 govern RIPK4 homeostasis via deubiquitination to enhance tumor metastasis in ovarian cancer. [Abstract]2024 Jun;43(25):1885-1899. PMID: 38664501
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EMBO Mol Med2024 Jul;16(7):1704-1716. PMID: 38902433
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ACS Appl Mater InterfacesMultifunctional Plasma-Activated Alginate Dressing Potentiates the Moist Healing of Chronic Infected Wounds. [Abstract]2025 Aug 27;17(34):48111-48122. PMID: 40810284
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Cell RepProstate cancer cell-derived exosomal IL-8 fosters immune evasion by disturbing glucolipid metabolism of CD8+ T cell. [Abstract]2023 Nov 13;42(11):113424. PMID: 37963015
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Clin Exp Hypertens2026 Dec 31;48(1):2607404. PMID: 41447318
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J Ethnopharmacol2025 Jun 26:350:120002. PMID: 40412780
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J Agric Food ChemBisphenol A Promotes Ovarian Cancer Proliferation and Migration through the HK2/H3K18la/IGF2BP3 Sequential Regulatory Axis. [Abstract]2026 Apr 8;74(13):11132-11149. PMID: 41885081
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MoleculesViolet Phosphorene Nanosheets Induced the Death of Ovarian Cancer Cells by Modulating the Vitamin B6 Pathway. [Abstract]2025 Nov 19;30(22):4453. PMID: 41302509
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Cancers (Basel)2022 Sep 17;14(18):4507. PMID: 36139668
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J Cell Mol Med2024 Jul;28(14):e18575. PMID: 39048916
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EpigeneticsA novel lncRNA, Lnc21q22.11, suppresses gastric cancer growth by inhibiting MEK/ERK pathway. [Abstract]2025 Dec;20(1):2512764. PMID: 40456011
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J Med VirolSPOP inhibits HBV transcription and replication by ubiquitination and degradation of HNF1α. [Abstract]2023 Dec;95(12):e29254. PMID: 38018242
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Cancer Manag ResBioinformatics Analysis and Experimental Validation of Lactylation Related Genes in Lung Adenocarcinoma. [Abstract]2025 Sep 12:17:1947-1960. PMID: 40964497
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J Cardiovasc Transl ResThe SGLT2 Inhibitor Canagliflozin Reduces Atherosclerosis by Enhancing Macrophage Autophagy. [Abstract]2023 Oct;16(5):999-1009. PMID: 37126209
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STAR ProtocProtocol for linking enhanced interferon immunity to virus resistance in gene-knockout zebrafish. [Abstract]2024 Jun 26;5(3):103156. PMID: 38941183
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STAR ProtocA protocol to characterize zebrafish LGP2 as a dual regulator of IFN response during viral infection. [Abstract]2022 Dec 16;3(4):101844. PMID: 36595883
Storage
Stored at -20°C, and is stable for 1 year.
Components
| Cat. No. | Product Name | Package |
|---|---|---|
| HY-K1006-10 mL | Penicillin-Streptomycin (100×) , Sterile | 10 mL |
| HY-K1006-100 mL | Penicillin-Streptomycin (100×) , Sterile | 100 mL |