Intermediate of tranexamic Acid-13C2,15N
Intermediate of tranexamic Acid-13C2,15N (Aminomethylbenzoic acid-13C2,15N) is 13C and 15N labeled 4-(Aminomethyl)benzoic acid. 4-(Aminomethyl)benzoic acid is a competitive inhibitor of PepT1 and has antifibrinolytic activity.
For research use only. We do not sell to patients.
- Formula: C613C2H915NO2
- Molecular Weight:154.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 56-91-7
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Molecular Weight 154.14
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Formula C613C2H915NO2
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SMILES
O=[13C](C1=CC=C([13C]([H])([H])[15NH2])C=C1)O
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Synonyms
Aminomethylbenzoic acid-13C2,15N; α-Amino-p-toluic acid-13C2,15N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Darcel N P, et al. Activation of vagal afferents in the rat duodenum by protein digests requires PepT1[J]. The Journal of nutrition, 2005, 135(6): 1491-1495. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)