Altemicidin
Altemicidin is a monoterpene alkaloid originally isolated from S. sioyaensis with acaricidal and anticancer activities. It is acaricidal to two-spotted spider mites (T. urticae) in a greenhouse pot test at concentrations of 10 and 100 ppm. Altemicidin inhibits the growth of murine L1210 lymphocytic leukemia and IMC carcinoma cells (IC50s=0.84 and 0.82 μg/mL, respectively). It is toxic to mice with an LD50 value of 0.3 mg/kg.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 125399-82-8
- 分子式: C13H20N4O7S
- 分子量:376.39
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| L1210 | IC50 |
0.84 μM
Compound: 9
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Antiproliferative activity against mouse L1210 cells assessed as inhibition of cell proliferation incubated for 48 hrs by Coulter counter method
Antiproliferative activity against mouse L1210 cells assessed as inhibition of cell proliferation incubated for 48 hrs by Coulter counter method
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[PMID: 33160760] |
| L1210 | IC50 |
2.12 μM
Compound: 1
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Cytotoxicity against mouse L1210 cells assessed as growth inhibition after 48 hrs by coulter counter analysis
Cytotoxicity against mouse L1210 cells assessed as growth inhibition after 48 hrs by coulter counter analysis
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[PMID: 26035239] |
化学情報
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CAS 番号 125399-82-8
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分子量 376.39
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分子式 C13H20N4O7S
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SMILES
O=C(C[S](N)(=O)=O)N[C@@]1([C@@](CN2C)([H])[C@@](C(C(N)=O)=C2)([H])C[C@@H]1O)C(O)=O
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別名
(-)-Altemicidin
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Altemicidin 関連分類
HY-N10653 関連分類
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