Carbaryl-d7
Based on 1 Customer Validation
Carbaryl-d7 is the deuterium labeled Carbaryl (HY-B1315). Carbaryl is the inhibitor for acetylcholinesterase that inhibits the degradation of acetylcholine in the synaptic cleft, leads to the accumulation of acetylcholine and causes neurotoxicity. Carbaryl can be used as an insecticide.
For research use only. We do not sell to patients.
- Purity: 99%
- CAS No.: 362049-56-7
- Formula: C12H4D7NO2
- Molecular Weight:208.26
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 362049-56-7
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Unlabeled Cas 63-25-2
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Appearance Solid
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Molecular Weight 208.26
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Formula C12H4D7NO2
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Color White to off-white
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SMILES
CNC(OC1=C([2H])C([2H])=C([2H])C2=C1C([2H])=C([2H])C([2H])=C2[2H])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (274 KB)
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SDS (788 KB)
- English - EN (788 KB)
- Français - FR (788 KB)
- Deutsch - DE (788 KB)
- Norwegian - NO (788 KB)
- Español - ES (788 KB)
- Swedish - SV (788 KB)
- Italian - IT (788 KB)
- Portuguese - PT (788 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Nancy E Todd, et al. Effects of Sevin (Carbaryl Insecticide) on Early Life Stages of Zebrafish (Danio Rerio). Ecotoxicol Environ Saf. 2002 Oct;53(2):267-72. [Content Brief]
[3]. Blevins RD, et al., Effects of carbaryl and dieldrin on the growth,protein content, and phospholipid content of HeLa cells. J Agric Food Chem. 1975 May-Jun;23(3):377-82. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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