Avizakimab
Based on 1 Customer Validation
Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.69%
- CAS 番号: 2229685-51-0
- 分子量:145.2 kDa
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
IL-21
体外実験
Avizakimab (BOS161721) prevents IL-21 binding to the IL-21 receptor (IL-21R) and inhibits bioactivity[1].
Avizakimab inhibits the downstream signaling, plasma cell differentiation, and natural killer cell activation induced by IL-21 and suppressed antibody responses to keyhole limpet hemocyanin (KLH) antigen[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
臨床実験
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
遺伝子ID
アクセッション番号
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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Human IgG1 kappa
アプリケーション
ELISA, FACS, Functional assay
化学情報
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CAS 番号 2229685-51-0
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性状 Liquid
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分子量 145.2 kDa
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Color Colorless to light yellow
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SMILES
[Avizakimab]
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別名
BOS161721
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輸送条件
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
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データシート (256 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Avizakimab 関連分類
HY-P99451 関連分類
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