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HDAC1-IN-9

HDAC1-IN-9 (13c) is a HDAC1 inhibitor. HDAC1-IN-9 inhibits HDAC1 enzyme with an IC50 of 1.07 µM. HDAC1-IN-9 exhibits the highest anti-proliferative effect against HT-29 (human colon adenocarcinoma), with anIC50 of 1.78 μM. HDAC1-IN-9 induces substantial Apoptosis in HCT-116 (human colon cancer) cells. HDAC1-IN-9 possesses antiangiogenic property. HDAC1-IN-9 reduces the expression levels of VEGFR-2 and phosphorylated VEGFR-2 (pVEGFR-2) by approximately 80 %.

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  • 分子式: C17H17N3O3
  • 分子量:311.34
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • HDAC1-IN-9 Chemical Structure
    HDAC1-IN-9 構造式
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  • HDAC1-IN-9 Chemical Structure
    HDAC1-IN-9 Chemical Structure
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  • HDAC1-IN-9