Bisoctrizole
Based on 1 publication(s) in Google Scholar
Bisoctrizole is a broad-spectrum UVA/UVB absorber that belongs to the benzotriazole class of compounds. Bisoctrizole absorbs UV light through hydroxyphenyl groups, causing reversible electronic transitions, thereby converting light energy into heat energy, inhibiting UV-induced material or skin damage. Bisoctrizole is highly efficient in capturing UVA (320-400 nm) and some UVB (280-320 nm) radiation. Bisoctrizole delays the photodegradation of materials such as silicones, improving their UV aging resistance or enhancing the photoprotective ability of sunscreen products.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98.0%
- CAS No.: 103597-45-1
- 화학식: C41H50N6O2
- 분자량:658.87
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
Publications Citing Use of MedChemExpress (MCE) Bisoctrizole
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Biological Activity
Bisoctrizole (1%, 2%; 100, 200 h artificial aging) significantly improves the UV absorption capacity of silicone resin in the UV absorption experiment, without significant difference between the 1% and 2% concentration groups[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 103597-45-1
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Appearance Solid
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분자량 658.87
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화학식 C41H50N6O2
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Color White to off-white
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SMILES
OC1=C(N2N=C3C(C=CC=C3)=N2)C=C(C(C)(C)CC(C)(C)C)C=C1CC4=CC(C(C)(C)CC(C)(C)C)=CC(N5N=C6C(C=CC=C6)=N5)=C4O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (1)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
SRSF5-Mediated Alternative Splicing of M Gene is Essential for Influenza A Virus Replication: A Host-Directed Target Against Influenza Virus. [Abstract]2022 Dec;9(34):e2203088. PMID: 36257906
용액&용해도
Acetone : 1 mg/mL (1.52 mM; ultrasonic and warming and heat to 60°C)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (277 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Ahmed WA, et al. Effect of Bisoctrizole on Ultraviolet (UV) Absorption Properties of Silicone and Effect on Surface Roughness-An In Vitro Study. Indian J Dent Res. 2024 Apr 1;35(2):211-215. [Content Brief]
[2]. Ruscinc N, et al. Vaccinium myrtillus L. extract associated with octocrylene, bisoctrizole, and titanium dioxide: in vitro and in vivo tests to evaluate safety and efficacy. J Cosmet Dermatol. 2022 Oct;21(10):4765-4774. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Acetone | 1 mM | 1.5178 mL | 7.5888 mL | 15.1775 mL | 37.9438 mL |