TIPARP-IN-1
TIPARP-IN-1 (Compound 15) is a selective PARP7 (TIPARP) (2,3,7,8-Tetrachlorodiben-zo-p-dioxin(TCDD)-inducible PARP) inhibitor with an IC50 of 2.15 nM. TIPARP-IN-1 can restore IFN signaling pathway in tumors by inhibiting TIPARP. TIPARP-IN-1 selectively activates the anti-tumor immune response in the tumor microenvironment and avoids the production of systemic cytokines. TIPARP-IN-1 can be used for research of head and neck squamous cell carcinoma.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 3106183-96-1
- 화학식: C22H23F6N5O2
- 분자량:503.44
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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PARP7 2.15 nM (IC50) |
Chemical Information
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CAS No. 3106183-96-1
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분자량 503.44
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화학식 C22H23F6N5O2
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SMILES
O=C([C@H]1C[C@@H](CC2=CNC(C(C(F)(F)F)=C2)=O)C1)N(C[C@H]3C)CCN3C4=NC=C(C(F)(F)F)C=N4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TIPARP-IN-1 Related Classifications
HY-181027 Related Classifications
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