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Cat. No.: HY-106895A

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L-702958 hydrochloride

L-702958 hydrochloride is a potent hERG blocker (IC₅₀ = 14.3 nM). L-702958 hydrochloride can be used for research on arrhythmia.

For research use only. We do not sell to patients.

CAS No.: 136078-58-5
Formula: C₂₅H₂₈ClN₃O₄S
Molecular Weight:502.03

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

L-702958 hydrochloride Chemical Structure

CAS No.: 136078-58-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

L-702958 hydrochloride is a potent hERG blocker (IC₅₀ = 14.3 nM). L-702958 hydrochloride can be used for research on arrhythmia^[1].

Chemical Information

CAS No. 136078-58-5
Molecular Weight 502.03
Formula C₂₅H₂₈ClN₃O₄S
SMILES

O=C1CC2(CCN([C@H]3CC4=CC=C(C#N)C=C4CC3)CC2)OC5=C1C=C(NS(C)(=O)=O)C=C5.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Karczewski J, et al. Analogs of MK-499 are differentially affected by a mutation in the S6 domain of the hERG K+ channel. Biochem Pharmacol. 2009 May 15;77(10):1602-11. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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