L-Histidine dihydrochloride
Based on 4 publication(s) in Google Scholar
L-Histidine dihydrochloride is a histidine derivative.
For research use only. We do not sell to patients.
- CAS No.: 6027-02-7
- Formula: C6H11Cl2N3O2
- Molecular Weight:228.08
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) L-Histidine dihydrochloride
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Cell Proliferation/Viability Assay
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In Vivo Efficacy Study
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2D/3D Cell Culture and Differentiation
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Cell Proliferation/Viability Assay
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2D/3D Cell Culture and Differentiation
Biological Activity
Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6027-02-7
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Molecular Weight 228.08
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Formula C6H11Cl2N3O2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (4)
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Journal Impact Factor
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Most Recent
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Cancer Cell
Integrative plasma and fecal metabolomics identify functional metabolites in adenoma-colorectal cancer progression and as early diagnostic biomarkers. [Abstract]2024 Aug 12;42(8):1386-1400.e8. PMID: 39137727
L-Histidine dihydrochloride purchased from MedChemExpress. Usage Cited in: Cancer Cell. 2024 Aug 12;42(8):1386-1400.e8. [Abstract]
Cell viability on day 4 at OD570 of CRC cells treated with different concentrations of CRC-depleted L-histidine (0.5-10 mM).
L-Histidine dihydrochloride purchased from MedChemExpress. Usage Cited in: Cancer Cell. 2024 Aug 12;42(8):1386-1400.e8. [Abstract]
Experimental schematic and colonoscopy images. L-histidine (100 mM; 100 μL; i.g.; every other day) reduced tumor size and cell proliferation in ApcMin/+ mice.
L-Histidine dihydrochloride purchased from MedChemExpress. Usage Cited in: Cancer Cell. 2024 Aug 12;42(8):1386-1400.e8. [Abstract]
Colony formation assays after L-histidine (5 mM; 10 d) treatment.
L-Histidine dihydrochloride purchased from MedChemExpress. Usage Cited in: Cancer Cell. 2024 Aug 12;42(8):1386-1400.e8. [Abstract]
Cell viability at OD570 after L-histidine (5 mM; dissolved in PBS with 10% DMSO; 5 d) treatment.
L-Histidine dihydrochloride purchased from MedChemExpress. Usage Cited in: Cancer Cell. 2024 Aug 12;42(8):1386-1400.e8. [Abstract]
Colony formation assays after L-histidine (10 d) treatment.
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Redox Biol
Histidine metabolic reprogramming drives oxidative stress induced mtDNA release to promote necroptosis and airway inflammation in severe asthma. [Abstract]2026 Jun 27:95:104280. PMID: 42372708 -
Mol Med
Microbially produced imidazole propionate impairs prostate cancer progression through PDZK1. [Abstract]2025 Jan 16;31(1):14. PMID: 39819421 -
Amino Acids
Identification of amino acids metabolomic profiling in human plasma distinguishes lupus nephritis from systemic lupus erythematosus. [Abstract]2024 Sep 18;56(1):56. PMID: 39292313
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)