LG-121071
LG-121071 is an orally active and selective androgen receptor modulator with a Ki of 17 nM.
For research use only. We do not sell to patients.
- CAS No.: 179897-70-2
- Formula: C15H15F3N2O
- Molecular Weight:296.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CV-1 | EC50 |
4 nM
Compound: 4
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Agonist activity to the human androgen receptor (hAR) in CV-1 cells
Agonist activity to the human androgen receptor (hAR) in CV-1 cells
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[PMID: 10340624] |
| CV-1 | IC50 |
4580 nM
Compound: 4
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Antagonistic activity against human androgen receptor (hAR) in CV-1 cells using cotransfection assay
Antagonistic activity against human androgen receptor (hAR) in CV-1 cells using cotransfection assay
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[PMID: 10340624] |
| CV-1 | EC50 |
4.1 nM
Compound: 3c, LG121071
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Agonist activity at human androgen receptor expressed in CV1 cells by transcriptional activation assay
Agonist activity at human androgen receptor expressed in CV1 cells by transcriptional activation assay
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[PMID: 17439112] |
| CV-1 | IC50 |
>10000 nM
Compound: 3c, LG121071
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Antagonist activity at human androgen receptor expressed in CV1 cells by transcriptional activation assay
Antagonist activity at human androgen receptor expressed in CV1 cells by transcriptional activation assay
|
[PMID: 17439112] |
| CV-1 | EC50 |
4 nM
Compound: 8
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Agonist activity against Human Androgen receptor expressed in CV-1 cells
Agonist activity against Human Androgen receptor expressed in CV-1 cells
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[PMID: 9925725] |
| CV-1 | IC50 |
7481 nM
Compound: 8
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Antagonist activity against Human Androgen receptor expressed in CV-1 cells
Antagonist activity against Human Androgen receptor expressed in CV-1 cells
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[PMID: 9925725] |
Chemical Information
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CAS No. 179897-70-2
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Molecular Weight 296.29
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Formula C15H15F3N2O
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SMILES
O=C1NC2=C(C=C(C(CC)CCN3)C3=C2)C(C(F)(F)F)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LG-121071 Related Classifications
HY-103577 Related Classifications
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