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Cat. No.: HY-148608

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LysoPalloT-NH-amide-C3-ph-m-O-C11

LysoPalloT-NH-amide-C3-ph-m-O-C11 is an agonist for GPR174 with an EC₅₀ of 34 nM.

For research use only. We do not sell to patients.

CAS No.: 1778686-61-5
Formula: C₂₇H₄₇N₂O₉P
Molecular Weight:574.64

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (261 KB)

LysoPalloT-NH-amide-C3-ph-m-O-C11 Chemical Structure

CAS No.: 1778686-61-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

LysoPalloT-NH-amide-C3-ph-m-O-C11 is an agonist for GPR174 with an EC₅₀ of 34 nM^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293-A	EC₅₀	>1 μM Compound: 12	Agonist activity at P2Y10 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay Agonist activity at P2Y10 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay	[PMID: 25970039]

Chemical Information

CAS No. 1778686-61-5
Molecular Weight 574.64
Formula C₂₇H₄₇N₂O₉P
SMILES

OC([C@@H](N)[C@H](C)OP(OC[C@H](O)CNC(CCC1=CC(OCCCCCCCCCCC)=CC=C1)=O)(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (261 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sayama M, et al., Switching Lysophosphatidylserine G Protein-Coupled Receptor Agonists to Antagonists by Acylation of the Hydrophilic Serine Amine. J Med Chem. 2021 Jul 22;64(14):10059-10101. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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