m-PEG3-amido-C3-triethoxysilane
m-PEG3-amido-C3-triethoxysilane is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 2243566-45-0
- Formula: C17H37NO7Si
- Molecular Weight:395.56
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2243566-45-0
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Appearance Liquid
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Molecular Weight 395.56
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Formula C17H37NO7Si
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Color Colorless to light yellow
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SMILES
O=C(NCCC[Si](OCC)(OCC)OCC)CCOCCOCCOC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (126.40 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5281 mL | 12.6403 mL | 25.2806 mL | 63.2015 mL |
| 5 mM | 0.5056 mL | 2.5281 mL | 5.0561 mL | 12.6403 mL | |
| 10 mM | 0.2528 mL | 1.2640 mL | 2.5281 mL | 6.3202 mL | |
| 15 mM | 0.1685 mL | 0.8427 mL | 1.6854 mL | 4.2134 mL | |
| 20 mM | 0.1264 mL | 0.6320 mL | 1.2640 mL | 3.1601 mL | |
| 25 mM | 0.1011 mL | 0.5056 mL | 1.0112 mL | 2.5281 mL | |
| 30 mM | 0.0843 mL | 0.4213 mL | 0.8427 mL | 2.1067 mL | |
| 40 mM | 0.0632 mL | 0.3160 mL | 0.6320 mL | 1.5800 mL | |
| 50 mM | 0.0506 mL | 0.2528 mL | 0.5056 mL | 1.2640 mL | |
| 60 mM | 0.0421 mL | 0.2107 mL | 0.4213 mL | 1.0534 mL | |
| 80 mM | 0.0316 mL | 0.1580 mL | 0.3160 mL | 0.7900 mL | |
| 100 mM | 0.0253 mL | 0.1264 mL | 0.2528 mL | 0.6320 mL |
m-PEG3-amido-C3-triethoxysilane Related Classifications
HY-141407 Related Classifications
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