Monoamine Oxidase B inhibitor 2
Monoamine Oxidase B inhibitor 2 is a potent, reversible, orally active and selective monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.33 nM. Monoamine Oxidase B inhibitor 2 has antioxidant and anti-neuroinflammatory activities. Monoamine Oxidase B inhibitor 2 can across the blood-brain barrier (BBB), and can be used for Parkinson’s disease study.
For research use only. We do not sell to patients.
- CAS No.: 2807477-26-3
- Formula: C19H19FO3
- Molecular Weight:314.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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MAO-B 1.33 nM (IC50) |
MAO-A 1150 nM (IC50) |
In cellular experiments, Monoamine Oxidase B inhibitor 2 (compound 8f; 0.5-10.0 μM) could significantly decrease the production of NO and TNF-α in LPS-stimulated BV-2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2807477-26-3
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Molecular Weight 314.35
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Formula C19H19FO3
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SMILES
CCCCC1OC(C2=CC(OCC3=CC=C(C=C3)F)=CC=C21)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Monoamine Oxidase B inhibitor 2 Related Classifications
HY-143245 Related Classifications
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