Monoamine Oxidase B inhibitor 4
Based on 1 Customer Validation
Monoamine Oxidase B inhibitor 4 (compound 1l) is a selective inhibitor of human monoamine oxidase-B (hMAO-B) (IC50=8.3 nM). Monoamine Oxidase B inhibitor 4 also has anti-neuroinflammatory and low neurotoxicity. Monoamine Oxidase B inhibitor 4 can inhibit the release of NO, TNF-α and IL-1β stimulated by LPS and Aβ1-42, and can also attenuate Aβ(1-42)-induced cytotoxicity.
For research use only. We do not sell to patients.
- Purity: 99.80%
- CAS No.: 424794-91-2
- Formula: C15H11Cl2NO3
- Molecular Weight:324.16
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 8.3 nM (hMAO-B)[1]
Chemical Information
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CAS No. 424794-91-2
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Appearance Solid
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Molecular Weight 324.16
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Formula C15H11Cl2NO3
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Color White to off-white
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SMILES
ClC1=CC=C(NC(C2=CC=C(OCCO3)C3=C2)=O)C=C1Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (154.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0849 mL | 15.4245 mL | 30.8490 mL | 77.1224 mL |
| 5 mM | 0.6170 mL | 3.0849 mL | 6.1698 mL | 15.4245 mL | |
| 10 mM | 0.3085 mL | 1.5424 mL | 3.0849 mL | 7.7122 mL | |
| 15 mM | 0.2057 mL | 1.0283 mL | 2.0566 mL | 5.1415 mL | |
| 20 mM | 0.1542 mL | 0.7712 mL | 1.5424 mL | 3.8561 mL | |
| 25 mM | 0.1234 mL | 0.6170 mL | 1.2340 mL | 3.0849 mL | |
| 30 mM | 0.1028 mL | 0.5141 mL | 1.0283 mL | 2.5707 mL | |
| 40 mM | 0.0771 mL | 0.3856 mL | 0.7712 mL | 1.9281 mL | |
| 50 mM | 0.0617 mL | 0.3085 mL | 0.6170 mL | 1.5424 mL | |
| 60 mM | 0.0514 mL | 0.2571 mL | 0.5141 mL | 1.2854 mL | |
| 80 mM | 0.0386 mL | 0.1928 mL | 0.3856 mL | 0.9640 mL | |
| 100 mM | 0.0308 mL | 0.1542 mL | 0.3085 mL | 0.7712 mL |
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