1. Apoptosis NF-κB Anti-infection Metabolic Enzyme/Protease
  2. Apoptosis Keap1-Nrf2 Bacterial Quinone Reductase Oxidative Phosphorylation
  3. Moringa Extract

Moringa Extract is the extract of Moringa with antioxidative and antibacterial activity. Moringa Extract increases Nrf2 and NQO1 expression, scavenges radicals, reduces oxidative stress, inhibits growth of Staphylococcus aureus and Escherichia coli. Moringa Extract can be used for the research of dietary supplements, cosmetics, and natural water purification.

For research use only. We do not sell to patients.

Moringa Extract

Moringa Extract Chemical Structure

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Description

Moringa Extract is the extract of Moringa with antioxidative and antibacterial activity. Moringa Extract increases Nrf2 and NQO1 expression, scavenges radicals, reduces oxidative stress, inhibits growth of Staphylococcus aureus and Escherichia coli. Moringa Extract can be used for the research of dietary supplements, cosmetics, and natural water purification[1][2][3][4].

In Vitro

Moringa extract (0.05-0.2% (w/v); incubated at 42°C until pH 4.6, then stored at 4°C for up to 21 days) accelerates skimmed milk yogurt fermentation by promoting the growth of Streptococcus thermophilus, Lactobacillus acidophilus, and Bifidobacterium longum, enhances textural properties[1].
Moringa extract-supplemented yogurt (0.05-0.2% (w/v); 16 h pretreatment + 2 h H2O2 exposure, 18 h) reduces hydrogen peroxide-induced oxidative stress and increases the expression of antioxidant proteins Nrf2 and NQO1 in human colorectal epithelial HT-29 cells, with effects increasing in a concentration-dependent manner[1].
Moringa extract (24 h) exhibit concentration-dependent antibacterial activity against Escherichia coli and Staphylococcus aureus[2].
Moringa extract (25 mL per plant per application; applied once at 2 weeks after emergence, at 2 and 4 weeks after emergence, or every 2 weeks starting at 2 weeks after emergence until harvest) increases total dry matter yield, root dry weight, and plant height of greenhouse-grown common beans (Phaseolus vulgaris)[3].
Moringa extract (25 mL per plant per application; applied once at 2 weeks after emergence, at 2 and 4 weeks after emergence, or every 2 weeks starting at 2 weeks after emergence until harvest) does not significantly affect total dry matter yield, root dry weight, or plant height of greenhouse-grown maize (Zea mays) under the tested conditions[3].
Moringa extract (applied once at 2 weeks after transplanting, at 2 and 4 weeks after transplanting, or every 2 weeks starting at 2 weeks after transplanting until physiological maturity) increases seed yield of field-grown common beans (Phaseolus vulgaris)[3].
Moringa extract (applied once at 2 weeks after transplanting, at 2 and 4 weeks after transplanting, or every 2 weeks starting at 2 weeks after transplanting until physiological maturity) increases grain yield[3].
Moringa extract (1:32 (v/v); once at 2 weeks after emergence, at 2 and 4 weeks after emergence, every 2 weeks starting at 2 weeks after emergence) significantly increases above-ground dry matter yield, root dry matter weight, and plant height of greenhouse-grown Lycopersicon esculentum L. var. Rodade tomato plants[4].
Moringa extract (1:32 (v/v); once at 2 weeks after transplanting, at 2 and 4 weeks after transplanting, every 2 weeks starting at 2 weeks after transplanting until physiological maturity) significantly increases fresh fruit yield and number of stem branches of field-grown Lycopersicon esculentum L. var. Rodade tomato plants[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: Human colorectal epithelial HT-29 cells
Concentration: 0.05%; 0.1%; 0.2% (w/v)
Incubation Time: 16 h pretreatment + 2 h H2O2 exposure; 18 h
Result: Significantly decreased intracellular H2O2 levels in H2O2-stressed HT-29 cells, with the effect increasing in a concentration-dependent manner.
Markedly increased the expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and NAD(P)H quinone dehydrogenase 1 (NQO1) in HT-29 cells, with greater upregulation observed at higher moringa extract concentrations compared to control yogurt.
In Vivo

Moringa Extract (0.1-0.5 g; topical; every 2 days; up to 11 days) incorporated into polyacrylonitrile nanofibers achieves concentration-dependent wound closure efficacy in rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wistar rats (healthy, weight 150-200 g)[2]
Dosage: 0.1 g; 0.15 g; 0.2 g; 0.5 g (incorporated into 16 wt% polyacrylonitrile nanofiber dressings)
Administration: topical; every 2 days; up to 11 days
Result: Achieved 35% wound closure at day 1, 87% at day 4, and 95% at day 7 for 0.5 g moringa extract nanofibers.
Showed intermediate wound closure rates for 0.1 g, 0.15 g, and 0.2 g moringa extract nanofibers.
Demonstrated complete re-epithelialization and nearly intact collagen fiber arrangement in the dermis by day 11 for 0.5 g moringa extract nanofibers.
Exhibited concentration-dependent improvement in wound closure.
Appearance

Solid

Color

Yellow to brown

SMILES

[Moringa Extract]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Moringa Extract
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HY-N13254
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