N-Acetyl-S-(3,4-dihydroxybutyl)-L-cysteine
N-Acetyl-S-(3,4-dihydroxybutyl)-L-cysteine (Dihydroxybutyl mercapturic acid) is a biomarkersof 1,3-butadiene exposure. 1,3-Butadiene is a known human carcinogen present in cigarette smoke and in automobile exhaust.
For research use only. We do not sell to patients.
- CAS No.: 144889-50-9
- Formula: C9H17NO5S
- Molecular Weight:251.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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CAS No. 144889-50-9
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Molecular Weight 251.30
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Formula C9H17NO5S
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SMILES
O=C(O)[C@H](CSCCC(O)CO)NC(C)=O
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Synonyms
Dihydroxybutyl mercapturic acid; DHBMA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Park SL, Kotapati S, Wilkens LR, et al. 1,3-Butadiene exposure and metabolism among Japanese American, Native Hawaiian, and White smokers. Cancer Epidemiol Biomarkers Prev. 2014;23(11):2240-2249. [Content Brief]
[2]. Kotapati S, Matter BA, Grant AL, Tretyakova NY. Quantitative analysis of trihydroxybutyl mercapturic acid, a urinary metabolite of 1,3-butadiene, in humans. Chem Res Toxicol. 2011;24(9):1516-1526. [Content Brief]
[3]. Lin CY, Lee HL, Jung WT, Sung FC, Su TC. The association between urinary levels of 1,3-butadiene metabolites, cardiovascular risk factors, microparticles, and oxidative stress products in adolescents and young adults. J Hazard Mater. 2020;396:122745. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)