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Cat. No.: HY-N8919

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N-trans-Sinapoyltyramine

N-trans-Sinapoyltyramine is an alkaloid. N-trans-Sinapoyltyramine can be isolated from Lindera glauca Sieb Zucc.

For research use only. We do not sell to patients.

CAS No.: 200125-11-7
Formula: C₁₉H₂₁NO₅
Molecular Weight:343.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

N-trans-Sinapoyltyramine Chemical Structure

CAS No.: 200125-11-7

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Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

N-trans-Sinapoyltyramine is an alkaloid. N-trans-Sinapoyltyramine can be isolated from Lindera glauca Sieb Zucc^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>40 μM Compound: 25	Antiproliferative activity against human A549 cells after 3 days by SRB assay Antiproliferative activity against human A549 cells after 3 days by SRB assay	[PMID: 25241925]
BV-2	IC₅₀	>50 μM Compound: 28	Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 20 hrs by Griess assay Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 20 hrs by Griess assay	[PMID: 33822610]
DU-145	IC₅₀	>40 μM Compound: 25	Antiproliferative activity against human DU145 cells after 3 days by SRB assay Antiproliferative activity against human DU145 cells after 3 days by SRB assay	[PMID: 25241925]
HepG2	IC₅₀	>20 μg/mL Compound: trans-N-sinapoyltyramine	Growth inhibition of HepG2 cells Growth inhibition of HepG2 cells	[PMID: 17547458]
KB	IC₅₀	>40 μM Compound: 25	Antiproliferative activity against human KB cells after 3 days by SRB assay Antiproliferative activity against human KB cells after 3 days by SRB assay	[PMID: 25241925]
MCF7	IC₅₀	>40 μM Compound: 25	Antiproliferative activity against human MCF7 cells after 3 days by SRB assay Antiproliferative activity against human MCF7 cells after 3 days by SRB assay	[PMID: 25241925]
MDA-MB-231	IC₅₀	>40 μM Compound: 25	Antiproliferative activity against human MDA-MB-231 cells after 3 days by SRB assay Antiproliferative activity against human MDA-MB-231 cells after 3 days by SRB assay	[PMID: 25241925]
MDA-MB-231	IC₅₀	>50 μM Compound: 10; Tyrosol sinapamide	Antimigratory activity against human MDA-MB-231 cells expressing c-MET assessed as inhibition of HGF-induced cell migration incubated for 24 hrs by Giemsa staining based wound healing assay Antimigratory activity against human MDA-MB-231 cells expressing c-MET assessed as inhibition of HGF-induced cell migration incubated for 24 hrs by Giemsa staining based wound healing assay	[PMID: 27258622]
MDA-MB-231	IC₅₀	72.8 μM Compound: 10; Tyrosol sinapamide	Antiproliferative activity against human MDA-MB-231 cells expressing c-MET assessed as inhibition of HGF-induced cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells expressing c-MET assessed as inhibition of HGF-induced cell growth incubated for 72 hrs by MTT assay	[PMID: 27258622]
MDA-MB-468	IC₅₀	80.2 μM Compound: 10; Tyrosol sinapamide	Antiproliferative activity against human MDA-MB-468 cells expressing c-MET assessed as inhibition of HGF-induced cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-468 cells expressing c-MET assessed as inhibition of HGF-induced cell growth incubated for 72 hrs by MTT assay	[PMID: 27258622]
SK-BR-3	IC₅₀	>40 μM Compound: 25	Antiproliferative activity against human SK-BR-3 cells after 3 days by SRB assay Antiproliferative activity against human SK-BR-3 cells after 3 days by SRB assay	[PMID: 25241925]
WI-38	IC₅₀	>20 μg/mL Compound: trans-N-sinapoyltyramine	Growth inhibition of WI38 cells Growth inhibition of WI38 cells	[PMID: 17547458]
WI-38 VA13	IC₅₀	>20 μg/mL Compound: trans-N-sinapoyltyramine	Growth inhibition of VA13 cells Growth inhibition of VA13 cells	[PMID: 17547458]
ZR-75-1	IC₅₀	>40 μM Compound: 25	Antiproliferative activity against human ZR-75-1 cells after 3 days by SRB assay Antiproliferative activity against human ZR-75-1 cells after 3 days by SRB assay	[PMID: 25241925]

Chemical Information

CAS No. 200125-11-7
Molecular Weight 343.37
Formula C₁₉H₂₁NO₅
SMILES

O=C(NCCC(C=C1)=CC=C1O)/C=C/C(C=C2OC)=CC(OC)=C2O
Structure Classification
- Phenols
- Polyphenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chang Y C, et al. Alkaloids from Lindera glauca[J]. Journal of the Chinese Chemical Society, 2001, 48(4): 811-815. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Purity & Documentation
References

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N-trans-Sinapoyltyramine

High-Throughput Bioactive Compound Library

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

N-trans-Sinapoyltyramine Related Classifications

HY-N8919 Related Classifications