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Cat. No.: HY-P3852

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Neurokinin Receptor (393-407), rat

Name: Neurokinin Receptor (393-407), rat
Brand: MedChemExpress
SKU: HY-P3852
Availability: PreOrder

(Synonyms: SPR393-407)

Neurokinin Receptor (393-407), rat (SPR393–407) is a rat neurokinin 1 receptor (NK1R) fragment. NK1R is rapidly internalized by endocytosis and recycled to the plasma membrane when binding to substance P (SP). Neurokinin Receptor (393-407), rat can be used in the research of neurogenic inflammation.

For research use only. We do not sell to patients.

CAS No.: 153607-26-2
Formula: C₇₂H₁₁₃N₁₇O₂₆S₂
Molecular Weight:1696.90

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Neurokinin Receptor (393-407), rat Chemical Structure

CAS No.: 153607-26-2

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

IC₅₀ & Target

^[1]

NK1R

All Neurokinin Receptor Isoforms :

In Vitro

Neurokinin Receptor (393-407), rat (10 pM) inhibits 50% of ¹²⁵I-SPR393-407 binding to antiserum^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 153607-26-2
Molecular Weight 1696.90
Formula C₇₂H₁₁₃N₁₇O₂₆S₂
Synonyms

SPR393-407
Sequence Shortening

KTMTESSSFYSNMLA
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (261 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Nathan JD, et al. Capsaicin vanilloid receptor-1 mediates substance P release in experimental pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2001 Nov;281(5):G1322-8. [Content Brief]

[2]. Vigna SR, et al. Characterization of antibodies to the rat substance P (NK-1) receptor and to a chimeric substance P receptor expressed in mammalian cells. J Neurosci. 1994 Feb;14(2):834-45. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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