1. Metabolic Enzyme/Protease
  2. Factor Xa
  3. O-Desmethyl apixaban sulfate sodium

O-Desmethyl apixaban sulfate sodium 

Cat. No.: HY-100652A
Handling Instructions

O-Desmethyl apixaban sulfate sodium is a major circulating metabolite of Apixaban in humans. O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM.

For research use only. We do not sell to patients.

O-Desmethyl apixaban sulfate sodium Chemical Structure

O-Desmethyl apixaban sulfate sodium Chemical Structure

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Description

O-Desmethyl apixaban sulfate sodium is a major circulating metabolite of Apixaban in humans. O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM[1][2].

IC50 & Target

Ki: 58 μM (Factor Xa)[1]

Molecular Weight

547.52

Formula

C₂₄H₂₂N₅NaO₇S

SMILES

O=C(C1=NN(C2=CC=C(OS(=O)(O[Na])=O)C=C2)C3=C1CCN(C4=CC=C(N5C(CCCC5)=O)C=C4)C3=O)N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

O-Desmethyl apixaban sulfateFactor XaFxaCirculatingmetaboliteFXaInhibitorinhibitorinhibit

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Product name:
O-Desmethyl apixaban sulfate sodium
Cat. No.:
HY-100652A
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