Oxindolylalanine

Cat. No.: HY-W674285 Purity: 98.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Oxindolylalanine, a tryptophan analogue, is an inhibitor of tryptophan indole-lyase (K_i: 5 μM) and tryptophan synthase. Tryptophan indole-lyase is a bacterial enzyme which catalyzes the reversible formation of indole and ammonium pyruvate from L-tryptophan.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Oxindolylalanine 화학구조

CAS No. : 32999-55-6

사이즈	재고	수량
100 mg	해외재고보유	Estimated Time of Arrival: December 31
250 mg	해외재고보유	Estimated Time of Arrival: December 31
500 mg	해외재고보유	Estimated Time of Arrival: December 31
1 g	해외재고보유	Estimated Time of Arrival: December 31
5 g	견적 받기
10 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

분자량

220.22

화학식

C₁₁H₁₂N₂O₃

CAS No.

32999-55-6

Appearance

Solid

Color

White to off-white

SMILES

NC(C(O)=O)CC1C(NC2=C1C=CC=C2)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

용액&용해도

In Vitro:

DMSO : 2 mg/mL (9.08 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.5409 mL	22.7046 mL	45.4091 mL
5 mM	0.9082 mL	4.5409 mL	9.0818 mL
10 mM	---	---	---

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

순도&문서

Purity: 98.0%

Select Batch:

Data Sheet (275 KB) SDS (393 KB)

COA (254 KB) HNMR (133 KB)

Handling Instructions (2659 KB)

References

[1]. Phillips RS, Buisman AA, Choi S, Hussaini A, Wood ZA. The crystal structure of Proteus vulgaris tryptophan indole-lyase complexed with oxindolyl-L-alanine: implications for the reaction mechanism. Acta Crystallogr D Struct Biol. 2018;74(Pt 8):748-759. [Content Brief]

[2]. Phillips RS, Harris AP. Structural Basis of the Stereochemistry of Inhibition of Tryptophan Synthase by Tryptophan and Derivatives. Biochemistry. 2021;60(3):231-244. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.5409 mL	22.7046 mL	45.4091 mL	113.5228 mL
DMSO	5 mM	0.9082 mL	4.5409 mL	9.0818 mL	22.7046 mL