2. Metabolic Enzyme/Protease
  3. PCSK9
  4. PCSK9-IN-9

PCSK9-IN-9 is an isocoumarins of natural origin. PCSK9-IN-9 can inhibit proprotein convertase subtilisin-kexin type 9 (PCSK9), IDOL, and SREBP2 mRNA expression. PCSK9-IN-9 inhibits PCSK9 with an IC50 value of 11.9 μM.

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PCSK9-IN-9

PCSK9-IN-9 Chemische Struktur

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PCSK9-IN-9 Related Antibodies

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Beschreibung

PCSK9-IN-9 is an isocoumarins of natural origin. PCSK9-IN-9 can inhibit proprotein convertase subtilisin-kexin type 9 (PCSK9), IDOL, and SREBP2 mRNA expression. PCSK9-IN-9 inhibits PCSK9 with an IC50 value of 11.9 μM[1].

IC50 & Target

Proprotein convertase subtilisin-kexin type 9 (PCSK9)[1]
In Vitro

PCSK9-IN-9 (compound 1) (20 μM; 24 h) suppresses PCSK9 mRNA level without affecting the protein level in HepG2 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PCSK9-IN-9 Related Antibodies
Molekulargewicht

412.56

Formel

C26H36O4
SMILES

CCCCC/C=C\C/C=C\CCCCCCCC1=CC2=C(C(O)=CC(O)=C2)C(O1)=O
Structure Classification
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
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PCSK9-IN-9 Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PCSK9-IN-9PCSK9Proprotein convertase subtilisin/kexin type 9Inhibitorinhibitorinhibit

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