PD-1/PD-L1-IN-41
PD-1/ PD-L1-in-41 (Compound 5c) is a PD-L1 and PD-1 inhibitor with IC50 value of 10.2 nM.
For research use only. We do not sell to patients.
- Formula: C33H32ClN3O5
- Molecular Weight:586.08
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 10.2 nM (PD-1/PD-L1)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
11.6 μM
Compound: 5c
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Cytotoxicity against CHO cells expressing human PD-L1 assessed as cell viability measured after 24 hrs by MTT assay
Cytotoxicity against CHO cells expressing human PD-L1 assessed as cell viability measured after 24 hrs by MTT assay
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[PMID: 38442487] |
PD-1/PD-L1-IN-41 (Compound 5c) (100 μl; 24 h) EC50 for CHO-hPD-L1 cells is 11.6 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 586.08
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Formula C33H32ClN3O5
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SMILES
CC1=C(C=CC=C1C2=CC=C3OCCOC3=C2)COC4=CC(OCC5=CC(C#N)=NC=C5)=C(CN(CCO)C)C=C4Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PD-1/PD-L1-IN-41 Related Classifications
HY-162343 Related Classifications
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