PD-1/PD-L1-IN-53
PD-1/PD-L1-IN-53 (compound B3) is an inhibitor targeting PD-1/PD-L1 and VISTA signaling pathways. PD-1/PD-L1-IN-53 can be used in anti-cancer research.
For research use only. We do not sell to patients.
- CAS No.: 3024006-29-6
- Formula: C31H37N3O4
- Molecular Weight:515.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
26.2 nM
Compound: B3
|
Inhibition of Eu-tagged PD-1 (unknown origin)/C-terminal Fc fusion (human IgG1)/Avi-tagged biotinylated human PDL1 (19 to 239 residues) extracted from HEK293 cells interaction preincubated for 15 mins with PD-L1 followed by PD-1 addition and measured afte
Inhibition of Eu-tagged PD-1 (unknown origin)/C-terminal Fc fusion (human IgG1)/Avi-tagged biotinylated human PDL1 (19 to 239 residues) extracted from HEK293 cells interaction preincubated for 15 mins with PD-L1 followed by PD-1 addition and measured afte
|
[PMID: 39389791] |
Chemical Information
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CAS No. 3024006-29-6
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Molecular Weight 515.64
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Formula C31H37N3O4
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SMILES
OC1CCN(CC1)CCCOC2=CC=CC(C3=CC=C4N=C(OC4=C3)C5=CC=CC(CNCCO)=C5)=C2C
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)