pH630 Deep Red maleimide, Thiol Reactive
pH630 Deep Red maleimide, Thiol Reactive is a fluorescent labeling reagent combining pH responsiveness and thiol targeting capabilities. It combines pH sensitivity and thiol-specific labeling, primarily used for highly specific, low-background fluorescent labeling and imaging of thiol-containing biomolecules in acidic environments (Ex/Em = 630/650 nm).
For research use only. We do not sell to patients.
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
Biological Activity
pH630 Deep Red TFP Ester, Amine Reactive contains a maleimide group, which undergoes a specific Michael addition reaction with thiol-containing biomolecules (such as peptides, antibodies, and aptamers) at pH 6.5–7.5. This binding is very stable and does not easily dissociate after labeling. pH630 Deep Red maleimide, Thiol Reactive is pH sensitive; it emits almost no fluorescence (low background) at neutral conditions (pH 7.4). Its fluorescence signal is only activated and significantly enhanced when exposed to acidic environments (such as late endosomes and lysosomes, pH around 5.0).
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
SMILES
[pH630 Deep Red maleimide, Thiol Reactive]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
pH630 Deep Red maleimide, Thiol Reactive Related Classifications
HY-D3522 Related Classifications
Powered by Bioz