pH630 Deep Red TFP Ester, Amine reactive
pH630 Deep Red TFP Ester, Amine reactive is a fluorescent labeling reagent combining pH responsiveness and amine-targeting capabilities. It combines pH sensitivity and amine-specific labeling, primarily used for highly specific, low-background fluorescent labeling and imaging of primary amine-containing biomolecules in acidic environments (Ex/Em = 630/650 nm).
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
pH630 Deep Red TFP Ester, Amine Reactive: The active group of tetrafluorophenyl ester (TFP) can react with the primary amine group (-NH2) on biomolecules (such as proteins and antibodies) to form a stable covalent amide bond. pH630 Deep Red TFP Ester, Amine Reactive is pH sensitive; in a neutral environment (pH 7.4), it emits almost no fluorescence (low background). Its fluorescence signal is only activated and significantly enhanced when exposed to acidic environments (such as late endosomes and lysosomes, pH approximately 5.0).
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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SMILES
[pH630 Deep Red TFP Ester, Amine reactive]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)