PtdIns-(3)-P1 (1,2-dipalmitoyl) ammonium
PtdIns-(3)-P1 (1,2-dipalmitoyl) (Compound 7) ammonium is a derivative of phosphatidylinositol 3-phosphate (PtdIns(3)P). phosphatidylinositol 3-phosphate can bind to the FYVE domain of human EEA1 and act as a second messenger in cellular signaling and membrane trafficking. phosphatidylinositol 3-phosphate can stimulate ROS formation by regulating the neutrophil oxidase complex.
For research use only. We do not sell to patients.
- Formula: C41H86N2O16P2
- Molecular Weight:925.07
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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Molecular Weight 925.07
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Formula C41H86N2O16P2
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SMILES
CCCCCCCCCCCCCCCC(OC[C@@H](OC(CCCCCCCCCCCCCCC)=O)COP(O[C@@H]1[C@@H]([C@@H]([C@H]([C@@H]([C@H]1O)O)O)OP([O-])(O)=O)O)([O-])=O)=O.[NH4+].[NH4+]
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Synonyms
DPPI-3-P ammonium; PIP[3'](16:0/16:0) ammonium; PI(3)P (16:0/16:0) ammonium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Gokhale NA, et al. Phosphoinositide specificity of and mechanism of lipid domain formation by annexin A2-p11 heterotetramer. J Biol Chem. 2005 Dec 30;280(52):42831-40. [Content Brief]
[2]. Ellson CD, et al. PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40(phox). Nat Cell Biol. 2001 Jul;3(7):679-82. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)