(R)-2-Hydroxyglutaryl-CoA dehydratase

(R)-2-Hydroxyglutaryl-CoA dehydratase (EC 4.2.1.167) from the bacteria Acidaminococcus fermentans and Clostridium symbiosum are involved in the fermentation of L-glutamate. (R)-2-Hydroxyglutaryl-CoA dehydratase (EC 4.2.1.167) contains [4F-4S] clusters, FMNH2 and riboflavin. It must be activated by an activator protein. Once activated, it can catalyse many turnovers.

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