AIM2 Protein, Human (sf9, GST)
Based on 1 Customer Validation
AIM2 Protein, a member of the IFI20X/IFI16 family, exhibits potential regulatory functions in cell proliferation and tumorigenic reversion. Induced by interferon-gamma, AIM2 plays a key role in immune responses. Notably expressed in tissues like lymph node and appendix, AIM2 is a significant player in diverse cellular processes and immune-related functions. AIM2 Protein, Human (sf9, GST) is the recombinant human-derived AIM2 protein, expressed by Sf9 insect cells , with N-GST labeled tag.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
AIM2 Protein, a member of the IFI20X/IFI16 family, exhibits potential regulatory functions in cell proliferation and tumorigenic reversion. Induced by interferon-gamma, AIM2 plays a key role in immune responses. Notably expressed in tissues like lymph node and appendix, AIM2 is a significant player in diverse cellular processes and immune-related functions. AIM2 Protein, Human (sf9, GST) is the recombinant human-derived AIM2 protein, expressed by Sf9 insect cells , with N-GST labeled tag.
AIM2 Protein, a member of the IFI20X/IFI16 family, is implicated in tumorigenic reversion and has potential regulatory functions in cell proliferation. The expression of AIM2 is induced by interferon-gamma, emphasizing its involvement in immune responses. With biased expression observed in tissues such as lymph node (RPKM 9.4), appendix (RPKM 5.0), and five other tissues, AIM2 stands out as a key player in diverse cellular processes and immune-related functions.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag N-GST
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Accession
O14862/NP_004824.1 (M1-T343)
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Molecular Construction
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N-term
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GST
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AIM2 (M1-T343)
Accession # NP_004824.1 -
C-term
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Protein Length
Full Length
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Synonyms
AIM2; Interferon-Inducible Protein AIM2; Absent In Melanoma 2; Alternative Protein AIM2; PYHIN4
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AA Sequence
MESKYKEILLLTGLDNITDEELDRFKFFLSDEFNIATGKLHTANRIQVATLMIQNAGAVSAVMKTIRIFQKLNYMLLAKRLQEEKEKVDKQYKSVTKPKPLSQAEMSPAASAAIRNDVAKQRAAPKVSPHVKPEQKQMVAQQESIREGFQKRCLPVMVLKAKKPFTFETQEGKQEMFHATVATEKEFFFVKVFNTLLKDKFIPKRIIIIARYYRHSGFLEVNSASRVLDAESDQKVNVPLNIIRKAGETPKINTLQTQPLGTIVNGLFVVQKVTEKKKNILFDLSDNTGKMEVLGVRNEDTMKCKEGDKVRLTFFTLSKNGEKLQLTSGVHSTIKVIKAKKKT
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Predicted Molecular Mass
65.2 kDa
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Molecular Weight
Approximately 65 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution
Supplied as a 0.22 μm filtered solution of 50 mM Tris, 1 M NaCl, 10% Glycerol, pH 8.0.
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
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Data Sheet (237 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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