ALDH7A1 Protein, Human (His)
Based on 1 Customer Validation
ALDH7A1, a multifunctional enzyme, plays a crucial role in mediating protective effects. It metabolizes betaine aldehyde into betaine, acting as a significant cellular osmolyte and methyl donor. Furthermore, ALDH7A1 safeguards cells from oxidative stress by metabolizing various aldehydes derived from lipid peroxidation. Additionally, it participates in lysine catabolism. ALDH7A1 Protein, Human (His) is the recombinant human-derived ALDH7A1 protein, expressed by E. coli , with N-His labeled tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
ALDH7A1, a multifunctional enzyme, plays a crucial role in mediating protective effects. It metabolizes betaine aldehyde into betaine, acting as a significant cellular osmolyte and methyl donor. Furthermore, ALDH7A1 safeguards cells from oxidative stress by metabolizing various aldehydes derived from lipid peroxidation. Additionally, it participates in lysine catabolism. ALDH7A1 Protein, Human (His) is the recombinant human-derived ALDH7A1 protein, expressed by E. coli , with N-His labeled tag.
ALDH7A1, a versatile enzyme, plays a crucial role in mediating essential protective effects within cells. It catalyzes the conversion of betaine aldehyde to betaine, serving as a vital cellular osmolyte and methyl donor. Notably, ALDH7A1 functions as a protective shield against oxidative stress by metabolizing various aldehydes derived from lipid peroxidation. Furthermore, the enzyme actively participates in lysine catabolism, contributing to broader metabolic processes. Through its multifaceted activities, ALDH7A1 emerges as a key player in cellular defense mechanisms and essential metabolic pathways.
The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-His
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Accession
P49419-2 (S2-Q511)
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Molecular Construction
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N-term
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His
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ALDH7A1 (S2-Q511)
Accession # P49419-2 -
C-term
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Protein Length
Full Length of Isoform-2 Mature Protein
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Synonyms
ALDH7A1; PDE; Prev. ATQ1; 26g Turgor Protein Homolog; Alpha-Aminoadipic Semialdehyde Dehydrogenase; Delta1-Piperideine-6-Carboxylate Dehydrogenease; Delta1-Piperideine-6-Carboxylate Dehydrogenase; Aldehyde Dehydrogenase 7 Family, Member A1; Betaine Aldehy
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AA Sequence
STLLINQPQYAWLKELGLREENEGVYNGSWGGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKIWADIPAPKRGEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
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Molecular Weight
Approximately 56 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of 50 mM Tris-HCL, 500 mM NaCl, pH 8.0, 20% glycerol, 5% trehalose, 5% mannitol, 0.01% Tween80.
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (238 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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