CARHSP1 Protein, Human (His)

The CARHSP1 protein critically regulates post-transcriptional gene expression by binding to mRNA, affecting its stability and influencing RNA homeostasis.Furthermore, in vitro binding of CARHSP1 to single-stranded DNA demonstrates the versatility of the molecular interaction.CARHSP1 Protein, Human (His) is the recombinant human-derived CARHSP1 protein, expressed by E.coli , with N-6*His labeled tag.

The CARHSP1 Protein plays a crucial role in post-transcriptional gene regulation by binding to mRNA and modulating the stability of the target mRNA, highlighting its involvement in cellular processes related to RNA homeostasis. Additionally, CARHSP1 exhibits the capacity to bind single-stranded DNA in vitro, suggesting potential versatility in its molecular interactions. Structurally, the protein forms homodimers, indicating that its functional activity may be linked to its dimeric state. Furthermore, CARHSP1 interacts with STYX, emphasizing its association with specific binding partners and potential involvement in larger molecular complexes or signaling pathways.

Human

E. coli

N-6*His

Q9Y2V2 (M1-S147)

23589  [NCBI]

Full Length

MSSEPPPPPQPPTHQASVGLLDTPRSRERSPSPLRGNVVPSPLPTRRTRTFSATVRASQGPVYKGVCKCFCRSKGHGFITPADGGPDIFLHISDVEGEYVPVEGDEVTYKMCSIPPKNEKLQAVEVVITHLAPGTKHETWSGHVISS

Approximately 21 kDa

• 
  ≥ 95%, as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.22 μm filtered solution of 50 mM Tris-HCl, 300 mM NaCL, pH 7.4.
Note: For SPR assay, please replace the buffer. Primary amine components (e.g., Tris, imidazole) can affect protein-coupled chips.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.