CD72 Protein, Mouse (HEK293, hFc)
CD72 Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived CD72 protein, expressed by HEK293, with N-hFc tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Help & FAQs
Biological Activity
Description
CD72 Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived CD72 protein, expressed by HEK293, with N-hFc tag.
Background
CD72 emerges as a key participant in the orchestration of B-cell proliferation and differentiation. Operating as a homodimer with disulfide linkages, it forms associations with CD5, thereby contributing to intricate signaling networks within the B-cell context. Additionally, CD72 engages in interactions, particularly tyrosine phosphorylation, with the protein tyrosine phosphatase PTPN6/SHP-1, indicating its involvement in modulating cellular responses through intricate phosphorylation-based regulatory mechanisms. This highlights the multifaceted role of CD72 in the dynamic landscape of B-cell function and signaling.
Technical Parameters
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Species Mouse
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Source HEK293
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Tag N-hFc
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Accession
P21855-1 (R117-N354)
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Gene ID12517
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Molecular Construction
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N-term
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hFc
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Cd72 (R117-N354)
Accession # P21855-1 -
C-term
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Protein Length
Extracellular Domain
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Synonyms
CD72; LYB2; CD72 Molecule; B-Cell Differentiation Antigen CD72; CD72 Antigen; Lyb-2; CD72b
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AA Sequence
RYLQVSRQFQEGTRIWEATNSSLQQQLREKISQLGQKEVELQKARKELISSQDTLQEKQRTHEDAEQQLQACQAERAKTKENLKTEEERRRDLDQRLTSTRETLRRFFSDSSDTCCPCGWIPYQERCFYISHTLGSLEESQKYCTSLSSKLAAFDEPSKYYYEVSLPSGLEELLDRSKSYWIQMSKKWRQDSDSQSRHCVRIKTYYQKWERTISKCAELHPCICESEAFRFPDGINLN
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Predicted Molecular Mass
54.3 kDa
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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