CD98 Protein, Mouse (HEK293, His)
Based on 1 Customer Validation
CD98 is a multifunctional protein predicted to function as an amino acid transmembrane transporter and to have double-stranded RNA binding activity.It is involved in carboxylic acid transport and virus entry, acting upstream of the dsRNA response, suggesting that it has multiple functions.CD98 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD98 protein, expressed by HEK293 , with N-10*His labeled tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
CD98 is a multifunctional protein predicted to function as an amino acid transmembrane transporter and to have double-stranded RNA binding activity.It is involved in carboxylic acid transport and virus entry, acting upstream of the dsRNA response, suggesting that it has multiple functions.CD98 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD98 protein, expressed by HEK293 , with N-10*His labeled tag.
Background
CD98, a multifunctional protein, is predicted to possess amino acid transmembrane transporter activity and double-stranded RNA binding activity. Its involvement in carboxylic acid transport and viral entry into host cells, as well as its role upstream of response to exogenous dsRNA, highlights its diverse functions. CD98 is strategically located in the apical pole of neurons and is actively engaged in synaptic processes. Its expression spans various structures, including the alimentary system, brain, genitourinary system, hemolymphoid system gland, and spinal cord. The ubiquity of CD98 expression is evident in numerous tissues, such as the kidney, genital fat pad, and 28 other tissues, underscoring its importance in various physiological contexts. Elucidating the intricate roles of CD98 in transport, cellular entry, and synaptic function is essential for comprehending its contributions to cellular processes and potential implications in health and disease.
Verified Bioactivity
Measured by its binding ability in a functional ELISA. Immobilized Mouse CD98 at 2 μg/mL (100 μL/Well) can bind Anti-CD98 Antibody. The KD for this effect is 7.98 nM.
Technical Parameters
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Species Mouse
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Source HEK293
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Tag N-10*His
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Accession
NP_001154885.1 (A139-A565)
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Molecular Construction
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N-term
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10*His
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CD98 (A139-A565)
Accession # NP_001154885.1 -
C-term
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Protein Length
Partial
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Synonyms
SLC3A2; Solute Carrier Family 3 (Activators Of Dibasic And Neutral Amino Acid Transport), Member 2; Prev. MDU1; Solute Carrier Family 3 (Amino Acid Transporter Heavy Chain), Member 2; 4F2 Cell-Surface Antigen Heavy Chain; Monoclonal Antibody 44D7; Lymphoc
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AA Sequence
APRCRELPVQRWWHKGALYRIGDLQAFVGRDAGGIAGLKSHLEYLSTLKVKGLVLGPIHKNQKDEINETDLKQINPTLGSQEDFKDLLQSAKKKSIHIILDLTPNYQGQNAWFLPAQADIVATKMKEALSSWLQDGVDGFQFRDVGKLMNAPLYLAEWQNITKNLSEDRLLIAGTESSDLQQIVNILESTSDLLLTSSYLSNSTFTGERTESLVTRFLNATGSQWCSWSVSQAGLLADFIPDHLLRLYQLLLFTLPGTPVFSYGDELGLQGALPGQPAKAPLMPWNESSIFHIPRPVSLNMTVKGQNEDPGSLLTQFRRLSDLRGKERSLLHGDFHALSSSPDLFSYIRHWDQNERYLVVLNFRDSGRSARLGASNLPAGISLPASAKLLLSTDSARQSREEDTSLKLENLSLNPYEGLLLQFPFVA
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Molecular Weight
Approximately 60-70 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (238 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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