CD98 Protein, Mouse (HEK293, His)

CD98 is a multifunctional protein predicted to function as an amino acid transmembrane transporter and to have double-stranded RNA binding activity. It is involved in carboxylic acid transport and virus entry, acting upstream of the dsRNA response, suggesting that it has multiple functions. CD98 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD98 protein, expressed by HEK293 , with N-His, N-10*His labeled tag. The total length of CD98 Protein, Mouse (HEK293, His) is 427 a.a., with molecular weight of 60-80 kDa.

CD98, a multifunctional protein, is predicted to possess amino acid transmembrane transporter activity and double-stranded RNA binding activity. Its involvement in carboxylic acid transport and viral entry into host cells, as well as its role upstream of response to exogenous dsRNA, highlights its diverse functions. CD98 is strategically located in the apical pole of neurons and is actively engaged in synaptic processes. Its expression spans various structures, including the alimentary system, brain, genitourinary system, hemolymphoid system gland, and spinal cord. The ubiquity of CD98 expression is evident in numerous tissues, such as the kidney, genital fat pad, and 28 other tissues, underscoring its importance in various physiological contexts. Elucidating the intricate roles of CD98 in transport, cellular entry, and synaptic function is essential for comprehending its contributions to cellular processes and potential implications in health and disease.

Mouse

HEK293

N-His;N-10*His

NP_001154885.1 (A139-A565)

17254  [NCBI]

APRCRELPVQRWWHKGALYRIGDLQAFVGRDAGGIAGLKSHLEYLSTLKVKGLVLGPIHKNQKDEINETDLKQINPTLGSQEDFKDLLQSAKKKSIHIILDLTPNYQGQNAWFLPAQADIVATKMKEALSSWLQDGVDGFQFRDVGKLMNAPLYLAEWQNITKNLSEDRLLIAGTESSDLQQIVNILESTSDLLLTSSYLSNSTFTGERTESLVTRFLNATGSQWCSWSVSQAGLLADFIPDHLLRLYQLLLFTLPGTPVFSYGDELGLQGALPGQPAKAPLMPWNESSIFHIPRPVSLNMTVKGQNEDPGSLLTQFRRLSDLRGKERSLLHGDFHALSSSPDLFSYIRHWDQNERYLVVLNFRDSGRSARLGASNLPAGISLPASAKLLLSTDSARQSREEDTSLKLENLSLNPYEGLLLQFPFVA

60-80 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.