Slc3a2 - solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 Gene

Also Known as 4F2; Cd98; Ly10; Mdu1; 4F2HC; Ly-10; NACAE; Ly-m10; Mgp-2hc

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17254

Summary

Predicted to enable amino acid transmembrane transporter activity and double-stranded RNA binding activity. Predicted to be involved in carboxylic acid transport and viral entry into host cell. Predicted to act upstream of or within response to exogenous dsRNA. Located in apical pole of neuron. Is active in synapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and spinal cord. Orthologous to human SLC3A2 (solute carrier family 3 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc3a2 Products (3)

mRNA Protein Name
NM_001161413.2 NP_001154885.1 4F2 cell-surface antigen heavy chain isoform a
NM_001410771.1 NP_001397700.1 4F2 cell-surface antigen heavy chain isoform b
NM_008577.5 NP_032603.3 4F2 cell-surface antigen heavy chain isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9915839 MGI
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
9915839 MGI
Biological Process GO Annotation Evidence References Source
involved in L-leucine transport IDA
IDA: Inferred from direct assay
9915839 MGI
Cellular Component GO Annotation Evidence References Source
located in apical pole of neuron IDA
IDA: Inferred from direct assay
16399997 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
16399997 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
9915839 MGI
is active in synapse EXP
EXP: Inferred from Experiment
24534009 MGI
is active in synapse IDA
IDA: Inferred from direct assay
24534009 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

4F2 cell-surface antigen heavy chain

  • CD98 antigen

  • CD98 heavy chain

  • antigen identified by monoclonal antibodies 4F2

  • solute carrier family 3 member 2

  • type II transmembrane protein

Recombinant Slc3a2 Proteins

Cat. No. Product Name Accession Purity
HY-P75367 CD98 Protein, Mouse (HEK293, His) NP_001154885.1 (A139-A565) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13242 SLC3A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16997 Slc3a2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23440 Slc3a2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc3a2 NCBI NCBI:6520