CK1γ3 Protein, Human (Active, sf9)
The CK1γ3 protein is a serine/threonine protein kinase in the casein kinase family that prefers acidic proteins, including casein. It has broad substrate specificity and can phosphorylate a variety of proteins, affecting diverse cellular processes. CK1γ3 Protein, Human (sf9) is the recombinant human-derived CK1γ3 protein, expressed by sf9 insect cells , with tag free.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
The CK1γ3 protein is a serine/threonine protein kinase in the casein kinase family that prefers acidic proteins, including casein. It has broad substrate specificity and can phosphorylate a variety of proteins, affecting diverse cellular processes. CK1γ3 Protein, Human (sf9) is the recombinant human-derived CK1γ3 protein, expressed by sf9 insect cells , with tag free.
CK1γ3, a serine/threonine-protein kinase within the casein kinase family, is characterized by its distinctive preference for acidic proteins, with caseins among its favored substrates. This kinase exhibits broad substrate specificity, phosphorylating numerous proteins to influence diverse cellular processes. Notably, CK1γ3 actively participates in the intricate Wnt signaling pathway, contributing to the modulation of cellular responses. Additionally, it plays a regulatory role in fast synaptic transmission mediated by glutamate, indicating its involvement in synaptic processes and neurotransmitter signaling, as suggested by functional similarities with other members of the casein kinase family.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag Tag Free
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Accession
Q9Y6M4 (E2-K447)
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Gene ID1456
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Molecular Construction
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N-term
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CK1γ3 (E2-K447)
Accession # Q9Y6M4 -
C-term
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Protein Length
Partial
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Synonyms
CSNK1G3; Non-Specific Serine/Threonine Protein Kinase; Casein Kinase 1 Gamma 3; Casein Kinase 1, Gamma 3; Casein Kinase I Isoform Gamma-3; Casein Kinase I; CKI-Gamma 3; CSNK1G3L
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AA Sequence
ENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSKNQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETKCCCFFKRRKRKTIQRHK
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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