CKS2 Protein, Human

CKS2 protein intricately binds to TEK/TIE2 to regulate ANGPT1 signaling. Its binding induces receptor tyrosine phosphorylation, affecting downstream cellular responses. CKS2 Protein, Human is the recombinant human-derived CKS2 protein, expressed by E. coli , with tag free. The total length of CKS2 Protein, Human is 79 a.a., .

Angiopoietin-4 (ANGPT4) intricately engages with TEK/TIE2, exerting regulatory control over ANGPT1 signaling. Its binding to TEK/TIE2 has the potential to induce tyrosine phosphorylation of the receptor, thereby influencing downstream cellular responses. ANGPT4 plays a crucial role in fostering endothelial cell survival, enhancing cell migration, and promoting angiogenesis, contributing to the intricate orchestration of vascular processes. Structurally, ANGPT4 exists as a homodimer, with disulfide linkages ensuring molecular stability. The direct interaction with TEK/TIE2 underscores the significance of ANGPT4 in modulating key signaling pathways associated with vascular homeostasis and angiogenic responses.

Human

E. coli

Tag Free

P33552 (M1-K79)

1164

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.